Article
TP53 mutations in stage I gallbladder carcinoma with special attention to growth patterns.
European journal of cancer (Oxford, England : 1990) - 1 Jun 1997
Hanada K, Itoh M, Fujii K, Tsuchida A, Hirata M, Iwao T, Eguchi N, Sasaki T, Matsubara K, Kajiyama G
Abstract excerpt
32 stage I cases of gallbladder carcinoma (GC) were examined to evaluate TP53 mutations with special attention to growth patterns. Their growth patterns were classified into two types: polypoid (P-type) and flat (F-type). 16 cases of GC were classified as P-type and 16 as F-type. p53 immunohistochemistry was performed using a mouse monoclonal anti-p53 antibody. Mutations in exons 5-8 were examined by polymerase...
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