Article
Genetic and metabolic determinants of increased plasma plasminogen activator inhibitor-1 activity in children with renal transplants.
Pediatric nephrology (Berlin, Germany) - 1 Aug 2003
Aldámiz-Echevarría Luis, Sanjurjo Pablo, Vallo Alfredo, Aguirre Mireia, Pérez-Nanclares Gustavo, Gimeno Pilar, Rueda Miguel, Ruiz José Ignacio, Rodríguez-Soriano Juan
Abstract excerpt
Recent studies have shown that activity of plasminogen activator inhibitor-1 (PAI-1), a prothrombotic protein, may be increased in transplanted patients. The aim of the present investigation was to determine PAI-1 activity in pediatric recipients of renal transplants and to establish the relative contribution of both genetic and metabolic factors. In 29 children and adolescents with stable renal transplants, we...
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