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Article

Angiotensinogen, angiotensine converting enzyme and plasminogen activator inhibitor-1 gene polymorphism in chronic allograft dysfunction.

Molecular biology reports - 1 May 2009

Azarpira Negar, Bagheri M, Raisjalali Gh A, Aghdaie M H, Behzadi S, Salahi H, Rahsaz M, Darai M, Ashraf M J, Geramizadeh B

Abstract excerpt

Despite dramatic improvements in first-year patient and graft survival rates, chronic allograft dysfunction (CAD) remains the leading cause of late renal allograft loss, while current immunologic strategies have little effect on this condition. The renin-angiotensin system (RAS) plays an important role in progression of chronic renal disease. It was shown that plasminogen activator inhibitor-1 (PAI-1) functions...

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Source

Identifiers

PMID: 18454324
DOI: 10.1007/s11033-008-9262-z

Genes

CAD
ACE
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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