Article
Angiotensinogen and plasminogen activator inhibitor-1 gene polymorphism in relation to chronic allograft dysfunction.
Clinical transplantation - 1 Feb 2005
Reis Kadriye, Arinsoy Turgay, Derici Ulver, Gonen Sevim, Bicik Zerrin, Soylemezoglu Oguz, Yasavul Unal, Hasanoglu Enver, Sindel Sukru
Abstract excerpt
Chronic allograft dysfunction (CAD) is the most common cause of allograft failure in the long-term, and current immunologic strategies have little effect on this condition. The renin-angiotensin system (RAS) plays important roles progression of chronic renal disease. It is thought that plasminogen activator inhibitor-1 (PAI-1) functions in the RAS, in addition to involvement in thrombotic risk and fibrosis. This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
