Article
Plasminogen activator inhibitor-1 5G/5G genotype is a protecting factor preventing posttransplant diabetes mellitus.
Clinica chimica acta; international journal of clinical chemistry - 30 Jan 2011
Chang Horng-Rong, Yang Shun-Fa, Tsai Jen-Pi, Hsieh Ming-Chia, Wu Sheng-Wen, Tsai Hui-Ching, Hung Tung-Wei, Huang Jun-Huang, Lian Jong-Da
Abstract excerpt
OBJECTIVE: Plasminogen activator inhibitor 1 (PAI-1) is thought to play a role in the pathogenesis of obesity and insulin resistance. A connection between gestational diabetes mellitus and the functional -675 PAI-1 genotype has been reported. Therefore, we examined the role of the PAI-1 gene polymorphism in kidney transplant recipients. METHODS: A total of 376 kidney transplant recipients were prospectively...
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