Increased PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF-beta levels.

doi:10.1016/s0021-9150(98)00108-7

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Article

Increased PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF-beta levels.

Atherosclerosis - 1 Sept 1998

Byrne C D, Wareham N J, Martensz N D, Humphries S E, Metcalfe J C, Grainger D J

Abstract excerpt

Whether the post-prandial lipemic response is linked to potentially pro-atherogenic and/or prothrombotic changes in plasminogen activator inhibitor (PAI) and transforming growth factor-beta (TGF-beta) is uncertain. The aim of our study was to determine whether PAI-1 antigen and PAI activity were...

Topics

Aged
Alleles
Body Mass Index
Dietary Fats
Genotype
Humans
Male
Middle Aged
Plasminogen Activator Inhibitor 1
Plasminogen Inactivators
Postprandial Period
Promoter Regions, Genetic
Transforming Growth Factor beta
Triglycerides

Source

Open in PubMed

Identifiers

PMID: 9733214
DOI: 10.1016/s0021-9150(98)00108-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9733214-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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