Article
NudC is required for Plk1 targeting to the kinetochore and chromosome congression.
Current biology : CB - 25 Jul 2006
Nishino Michiya, Kurasawa Yasuhiro, Evans Randall, Lin Sue-Hwa, Brinkley Bill R, Yu-Lee Li-Yuan
Abstract excerpt
The equal distribution of chromosomes during mitosis is critical for maintaining the integrity of the genome. Essential to this process are the capture of spindle microtubules by kinetochores and the congression of chromosomes to the metaphase plate . Polo-like kinase 1 (Plk1) is a mitotic kinase...
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