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Article

Modulation of eukaryotic mRNA stability via the cap-binding translation complex eIF4F.

Journal of molecular biology - 10 May 2002

Ramirez Carmen Velasco, Vilela Cristina, Berthelot Karine, McCarthy John E G

Abstract excerpt

Decapping by Dcp1 in Saccharomyces cerevisiae is a key step in mRNA degradation. However, the cap also binds the eukaryotic initiation factor (eIF) complex 4F and its associated proteins. Characterisation of the relationship between decapping and interactions involving eIF4F is an essential step towards understanding polysome disassembly and mRNA decay. Three types of observation suggest how changes in the...

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PMID: 12054793
DOI: 10.1016/S0022-2836(02)00162-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Modulation of eukaryotic mRNA stability via the cap-binding translation complex eIF4F.PMID 12054793Read ↗

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