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Article

Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jul 2000

Cosentino G P, Schmelzle T, Haghighat A, Helliwell S B, Hall M N, Sonenberg N

Abstract excerpt

Ribosome binding to eukaryotic mRNA is a multistep process which is mediated by the cap structure [m(7)G(5')ppp(5')N, where N is any nucleotide] present at the 5' termini of all cellular (with the exception of organellar) mRNAs. The heterotrimeric complex, eukaryotic initiation factor 4F (eIF4F),...

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Identifiers

PMID: 10848587
DOI: 10.1128/MCB.20.13.4604-4613.2000
PMCID: PMC85860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10848587-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.PMID 10848587Read ↗

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Eukaryotic Translation Initiation Factors 4G and 4A from Saccharomyces cerevisiae Interact Physically and FunctionallySemantic proximity Read ↗

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The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding ProteinsSemantic proximity Read ↗

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Mutants of eukaryotic initiation factor eIF-4E with altered mRNA cap binding specificity reprogram mRNA selection by ribosomes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Characterization of yeast translation initiation factor 1A and cloning of its essential gene.Semantic proximity Read ↗

Binding of eukaryotic translation initiation factor 4E (eIF4E) to eIF4G represses translation of uncapped mRNA.Semantic proximity Read ↗

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