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Article

Association of neprilysin polymorphism with cerebral amyloid angiopathy.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 2003

Yamada M, Sodeyama N, Itoh Y, Takahashi A, Otomo E, Matsushita M, Mizusawa H

Abstract excerpt

OBJECTIVES: The risk of sporadic cerebral amyloid angiopathy (CAA) may be associated with genetic polymorphisms of molecules related to anabolism or catabolism of amyloid beta protein (Abeta). The authors investigated whether a polymorphism of the gene (NEP) coding for neprilysin, an enzyme catabolising Abeta, is associated with CAA. METHODS: The study analysed the GT repeat polymorphism in the enhancer/promoter...

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Share to Aged, 80 and over
Share to Apolipoproteins E
Share to Cerebral Amyloid Angiopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Techniques

Share to Membrane Proteins

Share to Neprilysin

Share to Promoter Regions, Genetic

Share to Receptor Protein-Tyrosine Kinases

Source

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Identifiers

PMID: 12754344
DOI: 10.1136/jnnp.74.6.749
PMCID: PMC1738486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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