Article
Two types of sporadic cerebral amyloid angiopathy.
Journal of neuropathology and experimental neurology - 1 Mar 2002
Thal Dietmar Rudolf, Ghebremedhin Estifanos, Rüb Udo, Yamaguchi Haruyasu, Del Tredici Kelly, Braak Heiko
Abstract excerpt
Cerebral amyloid angiopathy (CAA) is a type of beta-amyloidosis that occurs in leptomeningeal and cortical vessels of the elderly. In a sample of 41 CAA cases including 16 Alzheimer disease (AD) cases and 28 controls, we show that 2 types of sporadic CAA exist: The first type is characterized by immunohistochemically detectable amyloid beta-protein (Abeta) in cortical capillaries, leptomeningeal and cortical...
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