Article
Possible increased risk for Alzheimer's disease associated with neprilysin gene.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jun 2003
Clarimón J, Muñoz F J, Boada M, Tàrraga L, Sunyer J, Bertranpetit J, Comas D
Abstract excerpt
Neprilysin has recently been reported to be the major physiological Abeta-degradating enzyme. In this study we describe a new biallelic polymorphism in the 3'UTR of the neprilysin gene in a representative population sample. The (*)159C/C genotype was found to be associated with an increased risk...
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