Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy.

Journal of neurology, neurosurgery, and psychiatry - 1 May 2005

Hamaguchi T, Okino S, Sodeyama N, Itoh Y, Takahashi A, Otomo E, Matsushita M, Mizusawa H, Yamada M

Abstract excerpt

BACKGROUND: A recent study showed that transforming growth factor-beta1 (TGF-beta1) induces amyloid-beta deposition in cerebral blood vessels and meninges of a transgenic mouse model of Alzheimer's disease (AD), and that TGF-beta1 mRNA levels are correlated with cerebral amyloid angiopathy (CAA) in human AD brains. A T/C polymorphism at codon 10 in exon 1 of the TGF-beta1 gene has been reported to be associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Amyloid Angiopathy

Share to Severity of Illness Index

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Open in PubMed Open full text

Identifiers

PMID: 15834029
DOI: 10.1136/jnnp.2003.034454
PMCID: PMC1739647

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy.PMID 15834029Read ↗

A TGF-beta1 polymorphism association with dementia and neuropathologies: the HAAS.Semantic proximity Read ↗

Meta-analysis of the transforming growth factor-β1 polymorphisms and susceptibility to Alzheimer's disease.Semantic proximity Read ↗

+10 T/C polymorphisms in the gene of transforming growth factor-beta1 are associated with neurodegeneration and its clinical evolution.Semantic proximity Read ↗

Risk Factors for Cerebral Amyloid Angiopathy in the ElderlySemantic proximity Read ↗

The gene encoding transforming growth factor beta 1 confers risk of ischemic stroke and vascular dementia.Semantic proximity Read ↗

Role of the Transforming-Growth-Factor-β1 Gene in Late-Onset Alzheimer’s Disease: Implications for the TreatmentSemantic proximity Read ↗

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression.Semantic proximity Read ↗

Association studies of transforming growth factor-beta 1 and Alzheimer's disease.Semantic proximity Read ↗

Association between polymorphisms in transforming growth factor-β1 and sporadic Alzheimer's disease in a Chinese population.Semantic proximity Read ↗

Association of alpha1-antichymotrypsin polymorphism with cerebral amyloid angiopathy.Semantic proximity Read ↗

The haplotype of the TGFβ1 gene associated with cerebral infarction in Chinese.Semantic proximity Read ↗

Association study of three polymorphisms of TGF-beta1 gene with Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.