Article
A bipartite mechanism for ERK2 recognition by its cognate regulators and substrates.
The Journal of biological chemistry - 8 Aug 2003
Zhang Jialin, Zhou Bo, Zheng Chao-feng, Zhang Zhong-yin
Abstract excerpt
Mitogen-activated protein (MAP) kinases control gene expression in response to extracellular stimuli and exhibit exquisite specificity for their cognate regulators and substrates. We performed a structure-based mutational analysis of ERK2 to identify surface areas that are important for recogniti...
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