Article
Effect of Iron Treatment on Nickel Absorption and Gene Expression of the Divalent Metal Transporter (DMT1) by Human Intestinal Caco‐2 Cells
1 Mar 2003
Abstract excerpt
Divalent Metal Transporter 1 (DMT1) is a transmembrane transporter located at the apical membrane of enterocytes and implicated in the duodenal uptake of iron. Results from expression experiments in Xenopus oocytes indicate that DMT1 can mediate transport of a wide range of divalent metals other than iron. The aim of the present study was to examine the effect of iron treatment on the uptake and transepithelial...
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