Article
Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms.
Molecular biology of the cell - 1 Dec 2002
Tabuchi Mitsuaki, Tanaka Naotaka, Nishida-Kitayama Junko, Ohno Hiroshi, Kishi Fumio
Abstract excerpt
Divalent metal transporter 1 (DMT1) is responsible for dietary-iron absorption from apical plasma membrane in the duodenum and iron acquisition from the transferrin cycle endosomes in peripheral tissues. Two isoforms of the DMT1 transcript generated by alternative splicing of the 3' exons have be...
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