Article
Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein.
Immunology and cell biology - 1 Jun 2003
Lucas Marianne, Mashimo Tomoji, Frenkiel Marie-Pascale, Simon-Chazottes Dominique, Montagutelli Xavier, Ceccaldi Pierre-Emmanuel, Guénet Jean-Louis, Desprès Philippe
Abstract excerpt
Over the past 7 years, West Nile zoonosis has been an emerging concern for public health in Europe, Middle East and more recently in North America. West Nile virus causes epidemic outbreaks in humans and infected patients may exhibit severe neurological symptoms. Because susceptibility and sensitivity to West Nile virus infections may depend on host genetic factors, a mouse model has been established to...
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