Article
OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horses.
PloS one - 7 May 2010
Rios Jonathan J, Fleming Joann G W, Bryant Uneeda K, Carter Craig N, Huber John C, Long Maureen T, Spencer Thomas E, Adelson David L
Abstract excerpt
West Nile virus, first identified within the United States in 1999, has since spread across the continental states and infected birds, humans and domestic animals, resulting in numerous deaths. Previous studies in mice identified the Oas1b gene, a member of the OAS/RNASEL innate immune system, as a determining factor for resistance to West Nile virus (WNV) infection. A recent case-control association study...
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