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Article

Search for testicular cancer gene hits dead-end.

Cell cycle (Georgetown, Tex.) - 1 Sept 2005

Matin Angabin, Nadeau Joseph H

Abstract excerpt

Testicular germ cell tumors (TGCTs) are the first tumors where the cell of origin, and the time of transformation were precisely defined. TGCTs in mice originate from primordial germ cells (PGCs) and develop within the testis during fetal development. TGCTs occur at an appreciable frequency (5%) only in the 129 family of inbred strains of laboratory mice, suggesting strong genetic control. These developmental and...

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Share to Gene Expression Regulation, Neoplastic
Share to Genetic Predisposition to Disease
Share to Germ Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms, Germ Cell and Embryonal

Share to Sequence Analysis, DNA

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Source

Identifiers

PMID: 16082220
DOI: 10.4161/cc.4.9.1992

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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