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Article

Power evaluations for family-based tests of association with incomplete parental genotypes.

Genetics - 1 May 2003

Yang Qiong, Xu Xin, Laird Nan

Abstract excerpt

While a variety of methods have been developed to deal with incomplete parental genotype information in family-based association tests, sampling design issues with incomplete parental genotype data still have not received much attention. In this article, we present simulation studies with four genetic models and various sampling designs and evaluate power in family-based association studies. Efficiency depends...

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Identifiers

PMID: 12750350
DOI: 10.1093/genetics/164.1.399
PMCID: PMC1462535

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