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Article

Family-based association tests for genomewide association scans.

American journal of human genetics - 1 Nov 2007

Chen Wei-Min, Abecasis Goncalo R

Abstract excerpt

With millions of single-nucleotide polymorphisms (SNPs) identified and characterized, genomewide association studies have begun to identify susceptibility genes for complex traits and diseases. These studies involve the characterization and analysis of very-high-resolution SNP genotype data for hundreds or thousands of individuals. We describe a computationally efficient approach to testing association between...

Topics

Alcohol Oxidoreductases
Child, Preschool
Computer Simulation
DNA-Binding Proteins
Databases, Genetic
Female
Genetic Predisposition to Disease
Genetic Testing
Genome, Human
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Pedigree

Polymorphism, Single Nucleotide

Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 17924335
DOI: 10.1086/521580
PMCID: PMC2265659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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