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Article

Evaluation of methods accounting for population structure with pedigree data and continuous outcomes.

Genetic epidemiology - 1 Sept 2011

Peloso Gina M, Dupuis Josée, Lunetta Kathryn L

Abstract excerpt

Methods to account for population structure (PS) in genome-wide association studies have been well developed in samples of unrelated individuals, but when a sample is composed of families, the task of finding and accounting for PS is not as straight forward. Family-based tests that condition on parental genotypes or their sufficient statistics are immune to biases due to PS, but are known to have low power,...

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PMID: 21618600
DOI: 10.1002/gepi.20590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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