Article
Power calculations for a general class of family-based association tests: dichotomous traits.
American journal of human genetics - 1 Sept 2002
Lange Christoph, Laird Nan M
Abstract excerpt
Using large-sample theory, we present a unified approach to power calculations for family-based association tests. Currently available methods for power calculations are restricted to special designs or require approximations or simulations. Our analytical approach to power calculations is broadly applicable in many settings. We discuss power calculations for two scenarios that have high practical relevance and...
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