New genes that interact with lin-35 Rb to negatively regulate the let-60 ras pathway in Caenorhabditis elegans.

doi:10.1093/genetics/164.1.135

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Article

New genes that interact with lin-35 Rb to negatively regulate the let-60 ras pathway in Caenorhabditis elegans.

Genetics - 1 May 2003

Thomas Jeffrey H, Ceol Craig J, Schwartz Hillel T, Horvitz H Robert

Abstract excerpt

Previous studies have shown that a synthetic multivulva phenotype results from mutations in genes that antagonize the ras-mediated intercellular signaling system responsible for vulval induction in Caenorhabditis elegans. Synthetic multivulva mutations define two classes of genes, A and B, and a...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Down-Regulation
Gene Expression Regulation
Mutation
Repressor Proteins
ras Proteins

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