Article
Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2.
PLoS genetics - 25 Apr 2008
Kirienko Natalia V, McEnerney John D K, Fay David S
Abstract excerpt
LIN-35 is the sole C. elegans representative of the pocket protein family, which includes the mammalian Retinoblastoma protein pRb and its paralogs p107 and p130. In addition to having a well-established and central role in cell cycle regulation, pocket proteins have been increasingly implicated in the control of critical and diverse developmental and cellular processes. To gain a greater understanding of the...
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