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Mutations in Caenorhabditis briggsae identify new genes important for limiting the response to EGF signaling during vulval development.

Evolution & development - 1 Jan 2000

Sharanya Devika, Fillis Cambree J, Kim Jaeyoung, Zitnik Edward M, Ward Kelly A, Gallagher Molly E, Chamberlin Helen M, Gupta Bhagwati P

Abstract excerpt

Studies of vulval development in the nematode C. elegans have identified many genes that are involved in cell division and differentiation processes. Some of these encode components of conserved signal transduction pathways mediated by EGF, Notch, and Wnt. To understand how developmental mechanisms change during evolution, we are doing a comparative analysis of vulva formation in C. briggsae, a species that is...

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PMID: 25627712
DOI: 10.1111/ede.12105

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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