Article
Mutations in Caenorhabditis briggsae identify new genes important for limiting the response to EGF signaling during vulval development.
Evolution & development - 1 Jan 2000
Sharanya Devika, Fillis Cambree J, Kim Jaeyoung, Zitnik Edward M, Ward Kelly A, Gallagher Molly E, Chamberlin Helen M, Gupta Bhagwati P
Abstract excerpt
Studies of vulval development in the nematode C. elegans have identified many genes that are involved in cell division and differentiation processes. Some of these encode components of conserved signal transduction pathways mediated by EGF, Notch, and Wnt. To understand how developmental mechanis...
Topics
- Animals
- Caenorhabditis
- Epidermal Growth Factor
- Female
- Mitogen-Activated Protein Kinase Kinases
- Mutation
- Signal Transduction
- Vulva