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Article

TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2005

Berdeli Afig, Celik Handan Ak, Ozyürek Ruhi, Dogrusoz Buket, Aydin Hikmet Hakan

Abstract excerpt

The recently described family of toll-like receptors (TLRs) is a key player in host immunity by mediating inflammatory reactions against a wide range of pathogens. Mutations and polymorphisms in TLRs have revealed the importance of TLRs in human defence against diseases. TLR-2 is reported to inte...

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Identifiers

PMID: 15968536
DOI: 10.1007/s00109-005-0677-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15968536-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children.PMID 15968536Read ↗

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