Article
Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution.
Development (Cambridge, England) - 1 Sept 2004
Bullock Simon L, Stauber Michael, Prell Alexander, Hughes Julian R, Ish-Horowicz David, Schmidt-Ott Urs
Abstract excerpt
Establishment of segmental pattern in the Drosophila syncytial blastoderm embryo depends on pair-rule transcriptional regulators. mRNA transcripts of pair-rule genes localise to the apical cytoplasm of the blastoderm via a selective dynein-based transport system and signals within their 3'-untran...
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