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Article

Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype.

The Journal of cell biology - 1 Oct 1994

Kislauskis E H, Zhu X, Singer R H

Abstract excerpt

We have characterized the structure and function of RNA sequences that direct beta-cytoplasmic actin mRNA to the cell periphery were mapped to two segments of 3'-untranslated region by expression of LacZ/beta-actin chimeric mRNAs in chicken embryo fibroblasts (CEFs). A 54-nt segment, the "RNA zipcode," and a homologous but less active 43-nt segment each localized beta-galactosidase activity to the leading...

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Identifiers

PMID: 7929587
DOI: 10.1083/jcb.127.2.441
PMCID: PMC2120214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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