Article
A genome scan for loci linked to quantitative insulin traits in persons without diabetes: the Framingham Offspring Study.
Diabetologia - 1 Apr 2003
Panhuysen C I M, Cupples L A, Wilson P W F, Herbert A G, Myers R H, Meigs J B
Abstract excerpt
AIMS/HYPOTHESIS: Hyperinsulinaemia and insulin resistance usually precede clinical hyperglycaemia and Type 2 diabetes. Thus, plasma insulin concentrations and insulin resistance are important quantitative traits associated with risk of Type 2 diabetes, and represent key measures for genetic analysis of the syndrome. METHODS: We carried out a genome-wide search for loci related to plasma insulin concentrations and...
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