Article
An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study.
Diabetes - 1 Apr 2005
Chiu Yen-Feng, Chuang Lee-Ming, Hsiao Chin-Fu, Hung Yi-Jen, Lin Ming-Wei, Chen Ying-Tsung, Grove John, Jorgenson Eric, Quertermous Thomas, Risch Neil, Hsiung Chao A
Abstract excerpt
Type 2 diabetes is a complex disease involving both genetic and environmental components. Abnormalities in insulin secretion and insulin action usually precede the development of type 2 diabetes and can serve as good quantitative measures for genetic mapping. We therefore undertook an autosomal genomic search to locate the quantitative trait locus (QTL) linked to these traits in 1,365 nondiabetic Chinese subjects...
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