Article
Apolipoproteins E and C1 and brain morphology in memory impaired elders.
Neurogenetics - 1 Apr 2003
Serra-Grabulosa J M, Salgado-Pineda P, Junqué C, Solé-Padullés C, Moral P, López-Alomar A, López T, López-Guillén A, Bargalló N, Mercader J M, Clemente I C, Bartrés-Faz D
Abstract excerpt
Previous research has shown that polymorphisms of the apolipoproteins E ( APOE) and APOC1 represent genetic risk factors for dementia and for cognitive impairment in the elderly. The brain mechanisms by which these genetic variations affect behavior or clinical severity are poorly understood. We studied the effect of APOE and APOC1 genes on magnetic resonance imaging measures in a sample of 50 subjects with...
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