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Article

MRI and genetic correlates of cognitive function in elders with memory impairment.

Neurobiology of aging - 1 Jan 2000

Bartrés-Faz D, Junqué C, Clemente I C, Serra-Grabulosa J M, Guardia J, López-Alomar A, Sánchez-Aldeguer J, Mercader J M, Bargalló N, Olondo M, Moral P

Abstract excerpt

The present study investigated the relationship between genetic variation, MRI measurements and neuropsychological function in a sample of 58 elders exhibiting memory decline. In agreement with previous reports, we found that the epsilon4 allele of the apolipoprotein E (APOE) and the D allele of the angiotensin converting enzyme (ACE) polymorphisms negatively modulated the cognitive performance. Further, we found...

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Source

Identifiers

PMID: 11378252
DOI: 10.1016/s0197-4580(01)00207-x

Genes

APOC1
ACE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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