Article
Apolipoprotein E e4 allele in the normal elderly: neuropsychologic and brain MRI correlates.
Clinical genetics - 1 Nov 1996
Schmidt H, Schmidt R, Fazekas F, Semmler J, Kapeller P, Reinhart B, Kostner G M
Abstract excerpt
The presence of the apolipoprotein E e4 allele has been considered to be a risk factor for Alzheimer's disease and vascular dementia. We therefore used demanding neuropsychologic testing and brain MRI to determine if elderly normals with at least one e4 allele demonstrate subclinical changes in cognition and a higher frequency of brain atrophy or silent ischemic brain damage. The study population consisted of 214...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.