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Article

Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis.

Rheumatology (Oxford, England) - 1 Jun 2003

Cope A P

Abstract excerpt

Experimental models seeking to explore how susceptible individuals develop rheumatoid arthritis (RA) propose that genetic and environmental factors shape a complex series of molecular and cellular interactions leading to a chronic inflammatory response. T lymphocytes and MHC class II genes have featured prominently in these models. More recent studies have suggested that perpetuation of inflammation in a...

Topics

Animals
Arthritis, Rheumatoid
Autoimmunity
Chronic Disease
Disease Progression
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12730506
DOI: 10.1093/rheumatology/keg262

Genes

TNF

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