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Article

Cytokines pre-determined by genetic factors are involved in pathogenesis of Rheumatoid arthritis.

Cytokine - 1 Oct 2015

Taneja Veena

Abstract excerpt

Rheumatoid arthritis (RA) is associated with the presence of autoreactive CD4 T cells that produce pro-inflammatory cytokines. The role of genetic factors in the predilection to develop RA is strongly supported by the increased presence of certain HLA class II molecules in patients. The HLA class II genes are highly polymorphic and are critical for generating an immune response to clear infections. Production of...

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Identifiers

PMID: 25541434
DOI: 10.1016/j.cyto.2014.11.028
PMCID: PMC4476951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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