Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of HLA class II genes in susceptibility/resistance to inflammatory arthritis: studies with humanized mice.

Immunological reviews - 1 Jan 2010

Taneja Veena, David Chella S

Abstract excerpt

Predisposition to develop rheumatoid arthritis (RA) has been associated with certain human leukocyte antigen (HLA) class II molecules, although the mechanism is still unknown. Various experimental animal models of inflammatory arthritis have been studied to address the role of major histocompatibility complex (MHC) genes in pathogenesis. We have generated transgenic mice expressing HLA class II molecules (DR and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Experimental
Share to Arthritis, Rheumatoid
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Citrulline

Share to Collagen

Share to Epitopes

Share to HLA-DQ Antigens

Share to Protein Processing, Post-Translational

Source

Identifiers

PMID: 20192993
DOI: 10.1111/j.0105-2896.2009.00858.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of HLA class II genes in susceptibility/resistance to inflammatory arthritis: studies with humanized mice.PMID 20192993Read ↗

To B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice.Semantic proximity Read ↗

HLA class II transgenic mice as models of human diseasesSemantic proximity Read ↗

HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis.Semantic proximity Read ↗

HLA transgenic mice as humanized mouse models of disease and immunity.Semantic proximity Read ↗

An HLA-DR1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II CollagenSemantic proximity Read ↗

Mechanism by which HLA-DR4 regulates sex-bias of arthritis in humanized mice.Semantic proximity Read ↗

New humanized HLA-DR4-transgenic mice that mimic the sex bias of rheumatoid arthritis.Semantic proximity Read ↗

Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis.Semantic proximity Read ↗

Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men.Semantic proximity Read ↗

Autoimmunity versus tolerance: analysis using transgenic mice.Semantic proximity Read ↗

Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age.Semantic proximity Read ↗

[Autoimmune-associated MHC class II molecules].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.