Article
Distance from the chromosome end determines the efficiency of double strand break repair in subtelomeres of haploid yeast.
Journal of molecular biology - 9 May 2003
Ricchetti Miria, Dujon Bernard, Fairhead Cécile
Abstract excerpt
Double strand break (DSB) repair plays an important role in chromosome evolution. We have investigated the fate of DSBs as a function of their location along the yeast chromosome XI, in a system where no conventional homologous recombination can occur. We report that the relative frequency of non-homologous endjoining (NHEJ), which is the exclusive mode of DSB repair in the internal chromosomal portion, decreases...
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