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Article

Increased risk of prostate cancer associated with AA genotype of cyclin D1 gene A870G polymorphism.

International journal of cancer - 1 Jan 2003

Wang Lizhong, Habuchi Tomonori, Mitsumori Kenji, Li Zhenhua, Kamoto Toshiyuki, Kinoshita Hidefumi, Tsuchiya Norihiko, Sato Kazunari, Ohyama Chikara, Nakamura Akira, Ogawa Osamu, Kato Tetsuro

Abstract excerpt

CCND1 mRNA is alternatively spliced to produce 2 transcripts, and the splicing pattern may be modulated by a frequent A870G single-nucleotide polymorphism within the conserved splice donor site of exon 4. Several studies have suggested a significant association between the CCND1 genotype and onset or progression of various cancers. To investigate the correlation of the polymorphism with genetic susceptibility to...

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Identifiers

PMID: 12455063
DOI: 10.1002/ijc.10793

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Increased risk of prostate cancer associated with AA genotype of cyclin D1 gene A870G polymorphism.PMID 12455063Read ↗

Cyclin D1 gene polymorphism and familial prostate cancer: the AA genotype of A870G polymorphism is associated with prostate cancer risk in men aged 70 years or older and metastatic stage.Semantic proximity Read ↗

Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis of 3,820 cases and 3,825 controls.Semantic proximity Read ↗

Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer.Semantic proximity Read ↗

Elevated risk of colorectal cancer associated with the AA genotype of the cyclin D1 A870G polymorphism in an Indian population.Semantic proximity Read ↗

Potential role of CCND1 G870A genotype as a predictor for urothelial carcinoma susceptibility and muscle-invasiveness in Taiwan.Semantic proximity Read ↗

CCND1 G870A polymorphism with altered cyclin D1 transcripts expression is associated with the risk of glioma in a Chinese population.Semantic proximity Read ↗

Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.Semantic proximity Read ↗

Specific CCND1 G870A alleles associated with breast cancer susceptibility: a meta-analysis of 5,528 cases and 5,353 controls.Semantic proximity Read ↗

Association of cyclin D1 genotype with breast cancer risk and survival.Semantic proximity Read ↗

The CCND1 G870A polymorphism and susceptibility to bladder cancer.Semantic proximity Read ↗

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Association between lncrna PCGEM1 polymorphisms and prostate cancer risk.Semantic proximity Read ↗

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