Article
Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor.
Journal of the National Cancer Institute - 15 Jan 1997
Ingles S A, Ross R K, Yu M C, Irvine R A, La Pera G, Haile R W, Coetzee G A
Abstract excerpt
BACKGROUND: Prostate cancer is an increasingly common disease for which there are few well-established risk factors. Family history data suggest a genetic component; however, the majority of prostate cancer cases cannot be explained by a single-gene model. Prostate cell division is influenced by two steroid hormones, testosterone and vitamin D, the action of each being mediated by its respective receptor. The...
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