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Article

MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk.

Carcinogenesis - 1 Dec 2005

Shen Jing, Terry Mary Beth, Gammon Marilie D, Gaudet Mia M, Teitelbaum Susan L, Eng Sybil M, Sagiv Sharon K, Neugut Alfred I, Santella Regina M

Abstract excerpt

O(6)-methylguanine DNA methyl-transferase (MGMT) is the only known critical gene involved in cellular defense against alkylating agents in the DNA direct reversal repair (DRR) pathway. Three single nucleotide polymorphism (SNP) coding for non-conservative amino acid substitutions have been identi...

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Source

Identifiers

PMID: 16014702
DOI: 10.1093/carcin/bgi179

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16014702-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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