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Article

Genetic damage by bifunctional agents in repair-active pre-meiotic stages of Drosophila males.

Mutation research - 1 Jul 2001

Wijen J P, Nivard M J, Vogel E W

Abstract excerpt

Most of our understanding of germline mutagenesis in Drosophila is based on the DNA repair-inactive, haploid post-meiotic stages. The diploid, repair-active pre-meiotic stages are more relevant to the situation encountered in somatic cells. DNA mono-adducts induced by agents like methyl methanesulphonate (MMS) and ethylene oxide (EO) are well repaired in the pre-meiotic cell stages, and these agents show...

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PMID: 11406175
DOI: 10.1016/s0027-5107(01)00124-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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