Article
Peroxisome proliferator-activated receptor alpha is involved in the regulation of lipid metabolism by ginseng.
British journal of pharmacology - 1 Apr 2003
Yoon Michung, Lee Hyunghee, Jeong Sunhyo, Kim Jung-Jae, Nicol Christopher J, Nam Kung Woo, Kim Moonza, Cho Byung Goo, Oh Goo Taeg
Abstract excerpt
1. Peroxisome proliferator-activated receptor alpha (PPARalpha) regulates the expression of the key genes involved in lipid metabolism following activation of this receptor by various ligands. Ginseng, a highly valuable medicine in oriental societies, is also reported to modulate lipid metabolism, although the mechanism of its action remains unknown. In order to test our hypothesis that ginseng exerts its effects...
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