Article
Dysregulation of gene expression within the peroxisome proliferator activated receptor pathway in morbidly obese patients.
Surgical endoscopy - 1 Jun 2009
Hindle A Katharine, Koury Jadd, McCaffrey Tim, Fu Sidney W, Brody Fred
Abstract excerpt
BACKGROUND: The causes of obesity are multifactorial but may include dysregulation of a family of related genes, such as the peroxisome proliferator activated receptor gamma (PPARgamma). When activated, the PPARgamma pathway promotes lipid metabolism. This study used microarray technology to evaluate differential gene expression profiles in obese patients undergoing bariatric surgery. METHODS: The study enrolled...
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