Article
Peroxisome proliferator activated receptors and obesity.
European journal of pharmacology - 12 Apr 2002
Kersten Sander
Abstract excerpt
The peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that govern numerous biological processes, including energy metabolism, cell proliferation, and inflammation. Three different PPAR isotypes can be distinguished: alpha, beta and gamma. PPARalpha is mainly present in liver where it has an important role in the regulation of nutrient metabolism, including...
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