Article
An efficient haplotyping method with DNA pools.
Nucleic acids research - 1 Aug 2002
Inbar Ester, Yakir Benjamin, Darvasi Ariel
Abstract excerpt
Determination of haplotype frequencies (the joint distribution of genetic markers) in large population samples is a powerful tool for association studies. This is due to their greater extent of polymorphism since any two bi-allelic single nucleotide polymorphisms (SNPs) generate a potential four-allele genetic marker. Therefore, a haplotype may capture a given functional polymorphism with higher statistical power...
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