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Article

Genetic and environmental factors in hereditary predisposition to tumors: a conceptual overview.

EXS - 1 Jan 2006

Hino Okio, Kobayashi Toshiyuki, Okimoto Kazuo

Abstract excerpt

Cancer is a heritable disorder of somatic cells. Carcinogenesis at the cellular level is like an opened Japanese fan, because initiated cells grow in several directions and tumors suggest the edge of the fan by having many gene abnormalities. We discuss here the primal force and gene networks (federal headship) in renal carcinogenesis. The Eker (Tsc2 mutant) rat model of hereditary renal carcinoma (RC) is an...

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PMID: 16383022
DOI: 10.1007/3-7643-7378-4_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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