Article
Mutations induced by reactive nitrogen oxide species in the supF forward mutation assay.
Mutation research - 30 May 2000
Routledge M N
Abstract excerpt
Nitric oxide is an important bioregulatory molecule with a range of physiological functions. Nitric oxide can also react with oxygen species to produce a range of reactive nitrogen oxides that can damage DNA and lead to mutations of the DNA base sequence. The mutagenicity of a variety of reactive nitrogen oxide species and related DNA damaging agents in the supF assay are reviewed here, in the context of recent...
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