Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutagenesis of the supF gene of pSP189 replicating in AD293 cells cocultivated with activated macrophages: roles of nitric oxide and reactive oxygen species.

Chemical research in toxicology - 1 Nov 2006

Kim Min Young, Wogan Gerald N

Abstract excerpt

Dysregulated production of nitric oxide (NO*) and reactive oxygen species by inflammatory cells contributes to mutagenesis and carcinogenesis. We have characterized mutagenesis in the target supF gene of pSP189 replicating in AD293 cells cocultivated with mouse macrophage-like RAW264.7 cells acti...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Coculture Techniques
Share to Genes, Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Peroxide

Share to Interferon-gamma

Share to Lipopolysaccharides

Share to Nitric Oxide

Share to RNA, Transfer

Source

Identifiers

PMID: 17112236
DOI: 10.1021/tx0601354

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17112236-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutagenesis of the supF gene of pSP189 replicating in AD293 cells cocultivated with activated macrophages: roles of nitric oxide and reactive oxygen species.PMID 17112236Read ↗

Mutations induced in the supF gene of pSP189 by hydroxyl radical and singlet oxygen: relevance to peroxynitrite mutagenesis.Semantic proximity Read ↗

Mutagenesis associated with nitric oxide production in macrophages.Semantic proximity Read ↗

Mutations induced by reactive nitrogen oxide species in the supF forward mutation assay.Semantic proximity Read ↗

Peroxynitrite-induced DNA damage in the supF gene: correlation with the mutational spectrum.Semantic proximity Read ↗

Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity.Semantic proximity Read ↗

Effects of peroxynitrite dose and dose rate on DNA damage and mutation in the supF shuttle vector.Semantic proximity Read ↗

Carbon dioxide modulation of peroxynitrite-induced mutagenesis of the supF gene in pSP189.Semantic proximity Read ↗

[NO-induced mutagenesis for microbial pathogen and host defense suppression].Semantic proximity Read ↗

Viral mutation accelerated by nitric oxide production during infection in vivo.Semantic proximity Read ↗

Spontaneous mutation spectra in supF: comparative analysis of mammalian cell line base substitution spectra.Semantic proximity Read ↗

Role of free radicals in viral pathogenesis and mutation.Semantic proximity Read ↗

Mutations at G:C base pairs predominate after replication of peroxyl radical-damaged pSP189 plasmids in human cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.