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Article

Theoretical rationale for the use of sequential single-drug antiretroviral therapy for treatment of HIV infection.

AIDS (London, England) - 2 May 2003

Phillips Andrew N, Youle Michael S, Lampe Fiona, Johnson Margaret, Sabin Caroline A, Lepri Alessandro Cozzi, Loveday Clive

Abstract excerpt

BACKGROUND: Subpopulations of HIV with mutations associated with resistance to antiretroviral drugs often have reduced replicative capacity, so virus with resistance mutations for all existing and new antiretroviral drugs is likely to be appreciably impaired. Issues of toxicity, quality of life and economics mean that the simultaneous use of all these drugs in combination is unrealistic. We aimed to explore the...

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PMID: 12700450
DOI: 10.1097/00002030-200305020-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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